Transport of nanoparticles across the endothelial cell layer

Studies of how intravenously injected nanoparticles (NPs) enter tumours and are taken up by tumour cells have been discussed for more than three decades. Despite this, we still much to learn about interactions between NPs they can be transported across the endothelial cell layer. More studies required before firm conclusions drawn regarding contribution passive or energy dependent mechanisms transport over allowing reach solid tumours.